Intermediates in flavoprotein catalyzed hydroxylations
نویسندگان
چکیده
منابع مشابه
Biochemical and Biophysical Research Communications Intermediates in Flavoprotein Catalyzed Hydroxylations
INTERMEDIATES IN FLAVOPROTEIN CATALYZED HYDROXYLATIONS Barrie Entsch, Vincent Massey and David P. Ballou Department of Biological Chemistry, The University of Michigan Ann Arbor, Michigan 48104 Received November 21,1973 Summary The reaction of molecular oxygen with the complex of reduced p-hydroxybenzoate hydroxylase and 2,4-dihydroxybenzoate has been followed by rapid reaction techniques. Duri...
متن کاملMechanisms of flavoprotein-catalyzed reactions.
Flavoproteins are a class of enzymes catalyzing a very broad spectrum of redox processes by different chemical mechanisms. This review describes the best studied of these mechanisms and discusses factors possibly governing reactivity and specificity.
متن کاملDeazaflavins as mediators in light-driven cytochrome P450 catalyzed hydroxylations.
A light-driven deazaflavin-dependent direct enzyme regeneration system has been developed for a P450-BM3 catalyzed CH-activating hydroxylation, thereby avoiding the need for the expensive NADPH cofactor.
متن کاملImidazolidinone intermediates in prolinamide-catalyzed aldol reactions.
The reaction between acetone and 4-nitrobenzaldehyde catalyzed by aniline prolinamide 1 was studied in depth. Working in different solvents with equimolar amounts of reagents and monitoring the reaction by 1H NMR, we detected and identified several imidazolidinones, such as those of the acetone 4, the aldol products 5a and 5b, and aldehydes 10a and 10b. According to our results, these compounds...
متن کاملTunneling of intermediates in enzyme-catalyzed reactions.
A fascinating group of enzymes has been shown to possess multiple active sites connected by intramolecular tunnels for the passage of reactive intermediates from the site of production to the site of utilization. In most of the examples studied to date, the binding of substrates at one active site enhances the formation of a reaction intermediate at an adjacent active site. The most common inte...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biochemical and Biophysical Research Communications
سال: 1974
ISSN: 0006-291X
DOI: 10.1016/0006-291x(74)90798-0